Keselu is constipated patients often apply a kind of medicine, use remove the container thin end of the cover, the container thin end inserted into the anus, the liquid squeezed into the anus, a little while, the patient will come out of the stool, due to the quick effect, clinical constipation is used for emergencies. However, many people have this experience: the beginning of the use of Keseru, the effect can be, but after a period of time, the effect is not obvious. Even some people just started to use little effect. Why is this? There are two preparations of the common Kai Seilu, one containing sorbitol, magnesium sulfate: each 100 ml contains 45-50 grams of sorbitol (by weight), 10 grams of magnesium sulfate and an appropriate amount of preservatives. The other contains glycerol: 62.5 grams of glycerol per 100 milliliters. Although the composition of the two preparations are different, but the principle of action is basically the same, are the use of glycerol or sorbitol high concentration, that is, hypertonic effect, so that more water seepage into the intestinal lumen, so that the intestinal content of the volume increased, the intestinal tract was dilated to stimulate the intestinal wall, reflexively caused by the reaction of defecation, coupled with its lubricating effect, can make the stool easily discharged. Kefir de mechanism is mainly through the stimulation of the intestinal wall to cause defecation reflex to treat constipation, if often used, will make the defecation reflex zone to defecation stimulation of the excitement threshold is getting higher and higher, the formation of a kind of dependence on Kefir in order to solve the habit of defecation, over time, the rectum on the stimulation of the Kefir will have a tolerance, will feel the more the more no matter how to use. Old and weak, chronic constipation, or bedridden for a long time, slow peristalsis, feces in the intestinal tract accumulated for too long, the water is absorbed feces is very dry and hard, the formation of a large fecal pellet stored in the rectal pot-belly, the use of corkscrew only a small amount of fecal water discharged stools, traditional Chinese medicine, called this “hot knot bypass flow”, the patient frequently want to stool not to solve the pain is abnormal. Because the diameter of the dry hard fecal mass in the rectal pot-belly is larger than the outlet of the anal canal, or because too much fecal matter is accumulated in the rectal pot-belly, resulting in fecal impaction to the extent that there is no space for intestinal peristalsis, so the feces can not be discharged with the use of corkscrews. At this time, only the finger diagnosis will be dry hard fecal mass picking broken, pick out the hard end of the stool head, and then open the feces can be opened to open the feces. Need special reminder is that the use of corkscrew for constipation can only treat the “symptoms”, so only as a temporary relief of constipation pain “emergency measures”, such as after surgery, postpartum, digestive barium examination or temporary disruption of the regular life caused by constipation, with the use of Kesiclovir will be immediately effective. However, prolonged use will produce dependence. To prevent constipation from the root, it is best to develop good dietary habits and habits, eat more dietary fiber, vegetables and fruits, moderately increase the amount of exercise, and develop regular bowel habits. On weekdays, don’t hold back stools for a long time, once you have the urge to immediately solve the problem, often use your hands to massage the abdomen, self-massage in a clockwise direction to promote intestinal peristalsis. Constipation after the emergency Kesler, the symptoms still did not improve, should go to the hospital to check the cause, if necessary, but also under the guidance of the doctor to take proprietary Chinese medicine or identification of internal Chinese medicine.