The treatment of common bile duct stones traditionally uses common bile duct incision and T-tube drainage. With the development of minimally invasive surgical techniques, this procedure can be done laparoscopically, which greatly reduces the trauma and pain of patients, but the T-tube needs to be left in place for a long time after surgery, which greatly reduces the quality of life of patients. Modern endoscopic surgical techniques have again brought a new approach to the treatment of common bile duct stones, namely duodenoscopic sphincter of Oddiotomy for stone extraction (EST), which can spare patients the trauma of surgery and the pain of leaving a T-tube in place, but irreversibly disrupts the structure and function of the physiological bile-intestinal valve, the sphincter of Oddi. The search for a treatment that can spare the patient the pain of a T-tube without destroying the integrity of the sphincter of Oddi has been a research goal and a hot topic for biliary surgeons. After repeated design and demonstration, we carried out laparoscopic common bile duct extraction and one-stage suturing, which not only preserved the structural and functional integrity of the sphincter of Oddi for the patient, but also saved the patient from the pain of leaving the T-tube in place. The surgical protocol uses a preoperative duodenoscopic nasobiliary drainage tube, an ERBD tube or an intraoperative J-tube to replace the T-tube for a short period of time for intra-biliary decompression to ensure surgical safety. It has achieved good clinical results and is well received by patients. We were invited to present this procedure at the American Society of Laparoscopic and Endoscopic Surgeons in April this year, and the clinical study has been published in World J Surg, an international authoritative journal of surgery. The development of modern minimally invasive surgery has undergone several revolutionary changes, firstly, the emergence of laparoscopic technology has realized the transformation of surgical treatment from huge incisions to tiny pores, thus reducing the trauma and pain caused by huge incisions; secondly, the emergence of single-port laparoscopic technology has realized the maximum reduction of the number of pores, which brings not only the reduction of trauma and pain caused by the reduction of the number of pores, but also the reduction of the hidden pain. The third is the Natural Tract Endoscopic Surgery (NOTES), although its minimally invasive meaning is still controversial in academic circles, it is believed that with the improvement of people’s understanding, a scientific evaluation of the minimally invasive nature of this technique will be given. It gives a new meaning to the concept of “minimally invasive” from the reduction of the size and number of incisions to the preservation of organ structure and function.