Thrombocytosis formal medical name for primary thrombocythemia, playing interferon, should be alert to the emergence of side effects and adverse reactions, monitoring the function of the thyroid gland, should also be timely review of routine blood tests. 1. Adverse reactions: the use of interferon may appear adverse reactions, including flu-like symptoms, skin rash, hair loss, drowsiness, allergies, etc., interferon injection site pressure and pain, accompanied by erythema symptoms, the above symptoms should be adjusted in a timely manner to adjust the treatment program, such as to be reduced to stop interferon, etc.. 2. Thyroid function: some patients will have hypothyroidism, depression and other mental symptoms after using interferon, it is recommended to check the thyroid function before using interferon, and ask whether the patient has a history of mental illness. 3. Review of blood routine: blood routine should be followed up during the use of interferon. It is recommended that weekly checkups be conducted during the first month of the use of interferon, biweekly follow-ups during the second month, and once a month after the condition improves until the blood picture stabilizes, and follow-ups are conducted once every three months. In addition, interferon is prohibited for patients with severe liver and kidney function impairment and patients who are allergic to the product. In addition, patients should maintain a positive mindset, active treatment while cooperating with physicians targeted medication to reduce the toxic side effects of interferon.