Painful urination and pus is basically caused by poor control of inflammation in the urinary system, and the corresponding condition is accompanied by frequent urination, urinary urgency, as well as fever and other symptoms. Urinary system inflammation will cause mucosal edema, exudation, prolonged poor control will lead to a large number of local leukocyte accumulation, phagocytosis of pathogens, resulting in septic reaction, mucosal irritation will occur during urination, and accompanied by pus outflow, and some patients will also have fever and other symptoms. Apparent urinary pain and pus, and accompanied by abnormal urinary conditions, the need for timely admission to the hospital, if necessary, can do a drug sensitivity culture, after diagnosis of the specific conditions, under the guidance of the clinician to standardize the treatment, to avoid delays in the condition.