Osteoporosis Prevention and Treatment Lecture 1: How a fall can lead to a fracture

Shang Da-ma is 63 years old this year, usually quite good health, in the home to buy food to cook, send grandson to school, busy. Two months ago the rainy day Shang Aunt went out to buy vegetables, accidentally fell down, fortunately with the hands of the ground, did not fall directly to the ground, but climbed up to feel the pain of the left wrist, dare not move, the family rushed to the hospital, took an X-ray, the results of the diagnosis of the left wrist radius fracture, Shang Aunt is very puzzled, they are not just use their hands to support the body, how did the fracture? The doctor also gave Shang Auntie did a bone densitometry, found that Shang Auntie suffers from severe osteoporosis, this fracture is osteoporosis caused trouble. What is osteoporosis: Osteoporosis is a systemic metabolic bone disease, which is defined by the World Health Organization (WHO) as a systemic, systemic bone disease characterized by a decrease in bone mass and destruction of the microstructure of bone tissue, leading to an increase in bone brittleness and an increase in the risk of fracture. The most common is primary osteoporosis. Primary osteoporosis is a bone disease associated with aging and menopause in women, and can be characterized as a disease caused by degenerative changes in the bones that inevitably occur with age. To recognize osteoporosis it is important to understand the composition of the skeleton. Our bones are composed of bone matrix, which includes collagen and non-collagen proteins, and bone mineral salts, which are hydroxyapatite and other calcium salts formed from calcium and phosphorus. Bone matrix and bone mineral salts are bonded together like rebar and concrete to form hard, strong bones. Our bone tissue, like all other tissues in the body, is living tissue and undergoes its own growth and renewal as the body grows and develops. Bone tissue begins to accumulate bone mass from the fetal stage, and then continues to accumulate bone mass through infancy, childhood, adolescence, and into adulthood. After reaching a peak in bone mass around the age of 30, which we call peak bone mass, bone mass forms a plateau, and an age-related loss of bone mass begins around the age of 40. There is a rapid loss of bone mass in women after menopause, which is why women are more susceptible to osteoporosis, and of course, men also lose bone mass with age and are susceptible to osteoporosis after age 70. How do we lose bone mass, it is necessary to talk about the reconstruction of bones, bones are not static after maturity, but constantly metabolized, this metabolism of bones we call bone reconstruction, including two processes: bone resorption, bone formation, under normal circumstances, bone formation and bone resorption to maintain a dynamic balance, the amount of bone is also unchanged, if a variety of reasons lead to an increase in bone resorption or a decrease in the formation of bone will make the loss of bone mass. If bone resorption increases or bone formation decreases due to various reasons, it will lead to bone loss, which can cause osteoporosis in serious cases.