Recently, minimally invasive surgery successfully performed the first transumbilical single-hole laparoscopic cholecystectomy, making it a reality that no scar remains in the abdomen after cholecystectomy and achieving another leap in the application of laparoscopic surgery technology. Transumbilical single-port laparoscopic surgery is the most cutting-edge minimally invasive technology in the world. During the surgery, surgical instruments and equipment enter the abdominal cavity through the umbilical port and use the scar left after the closure of the umbilical port, which is the natural orifice of the human body, to perform the surgery, and the skin folds of the umbilicus can cover the incision, thus achieving the effect of scarless surgery. The transumbilical single-hole laparoscopic technique is the angle of traditional laparoscopic surgery changed from four-hole, three-hole or two-hole to one-hole, which poses a new challenge to the surgeon-in-chief in terms of experience and skills, and only a few hospitals in China can master this transumbilical single-hole laparoscopic minimally invasive technique in a mature way. Compared with traditional laparoscopic abdominal minimally invasive surgery, single-port laparoscopic cholecystectomy has outstanding characteristics of minimally invasive, safety, economy, aesthetics, and less postoperative pain.