High blood creatinine is a manifestation of kidney function impairment, if the kidney function impairment is greater than 50%-70% or more, clinical symptoms can appear. Some patients have no obvious symptoms, some patients can have weakness, poor appetite and other symptoms, further aggravation of the disease will have nausea, vomiting, dizziness, panic, breath-holding and other obvious symptoms. It can be chronic renal failure or acute renal failure, the latter is often accompanied by short-term oliguria and anuria, which may be life-threatening. Once high blood creatinine is detected, it should be actively treated and the condition should not be allowed to continue to spread. Active detection, early treatment, and active treatment of relevant aspects when the symptoms are relatively mild, to prevent further development and deterioration of the disease, are of great significance in treating the patient’s disease.