Patients wake up at one or two o’clock in the middle of the night and can’t sleep is a common manifestation of insomnia, the formation of the following reasons: 1, may be related to the patient’s habits, such as the patient’s sleep posture is incorrect or too full, too hungry, sleep too long during the day, drinking strong tea, strong coffee at bedtime can easily lead to the above problems; 2, consider the psychological factors related to the patient, such as the patient’s sleep environment Change or mental stress, excessive anxiety, tension, etc., also easily lead to patients waking up at one or two o’clock in the middle of the night and having difficulty falling asleep after waking up. Especially if the patient is too concerned and worried about insomnia, it is more likely to aggravate this problem; 3. It may be related to the patient’s age, which is also a major risk factor for insomnia as age increases, especially for menopausal women.