In general, megacolon is not self-healing. Megacolon is a morphologic diagnosis, mainly divided into congenital and acquired, congenital megacolon is mostly caused by intestinal nerve development disorders, while acquired megacolon is mainly due to inflammation, adhesion and other reasons. Patients with megacolon should pay attention to regulate diet, develop good bowel habits, can be operated by the doctor for saline enema, can also be used under the guidance of the doctor laxatives, such as lactulose, sorbitol, etc. for treatment, or the use of corkscrew for intestinal laxative treatment. Generally speaking, megacolon cannot be cured by itself. If the patient is not treated in time, it may lead to aggravation of constipation and affect the nutritional intake. For the conservative treatment effect is not obvious or the condition is more serious patients can improve the condition through surgical treatment.