Oral amoxicillin has no effect on mumps patients, because amoxicillin belongs to the antimicrobial agents, and mumps is not a bacterial infection, but a respiratory infectious disease caused by the mumps virus, which is mainly transmitted by droplets. The patient’s clinical symptoms are mainly parotid gland enlargement, first one side is enlarged, and then spread to the other side, the typical symptom is centered on the earlobe, expanding forward, backward and downward, and it is easy to combine with systemic fever. It mainly occurs in children and adolescents, and rarely occurs in adults. After suffering from mumps, patients can obtain long-lasting immunity, or even lifelong immunity, and reoccurrence is extremely rare.