Hepatitis B Penta quantitatively and the different combinations of the five have the significance to help clinically diagnose whether it is viral hepatitis B or not, and to determine the current status and regression of hepatitis B infection. Hepatitis B 5, also known as Hepatitis B 2.5, are Hepatitis B Surface Antigen (HBsAg), Hepatitis B Surface Antibody (anti-HBs), Hepatitis B e Antigen (HBeAg), Hepatitis B e Antibody (anti-HBe), and Hepatitis B Core Antibody (anti-HBc). The Hepatitis B two-half test detects serologic markers of the Hepatitis B virus in the blood. Different combinations of the five Hepatitis B tests are used to determine the status and regression of the infection. Among them, Hepatitis B e antigen and Hepatitis B core antibody, which can indicate the presence or absence of viral activity in the blood and an indicator of infectiousness. If items 1, 3 and 5 of the Hepatitis B Penta are positive and the remaining two items are negative, it is commonly known as Hepatitis B triple positive. If items 1, 4 and 5 of the Hepatitis B Penta are positive and the remaining two items are negative, it is commonly known as Hepatitis B Minor Triple Positive. In addition, the physician can determine if the test results indicate that the person needs to be vaccinated or supplemented with the Hepatitis B vaccine.