adp platelet maximal aggregation rate is very low may be platelet apheresis, in addition there may be uremia, cirrhosis, hypofibrinogenemia and so on caused by. adp, also known as adenosine diphosphate, is a substance produced during platelet activation and aggregation, which can lead to platelet aggregation and thus achieve the effect of coagulation. When the maximum aggregation rate of adp platelets decreases, the body will have a coagulation dysfunction, leading to a series of bleeding events. Clinically, it is common in platelet apoplexy, which cannot release adp effectively, while uremia, cirrhosis, hypofibrinogenemia, and long-term aspirin can also lead to a decrease in adp-induced platelet aggregation. In conclusion, the maximal aggregation rate of adp platelets is very low, and it is recommended to consult a hematologist for further investigation of the etiology.