The spread of liver cancer suggests that the disease has entered the advanced stage, and there is still a need for treatment. Radiotherapy and targeted therapy can be used to improve the quality of life and prolong the survival time of patients. Commonly used chemotherapeutic drugs include cisplatin, cyclophosphamide, vincristine, fluorouracil, cytarabine, etc. Targeted drugs used to treat liver cancer include lenvatinib, sorafenib and so on. These drugs can effectively shrink the tumor foci and slow down the growth and spreading process of the tumor, which can obviously improve the quality of life and prolong the survival time of patients. It is recommended that patients maintain a relaxed state of mind, actively cooperate with the doctor to receive standardized treatment, the adverse effects of the drug promptly consult a doctor, drug allergy is prohibited.