Nail groove inflammation perforated thumb anterior end, belongs to the local bacterial infection, can be through the general treatment, drug treatment, surgical treatment and other measures. 1. General treatment: keep the skin clean and hygienic, avoid extrusion, avoid excessive force, elevate the affected side of the limb, reduce the symptoms of localized swelling. 2. Drug treatment: local can wipe povidone-iodine, routine disinfection after topical antibiotic ointment, such as mupirocin ointment, fusidic acid cream, etc.; serious can be intravenous drip penicillin, or take cefaclor, amoxicillin and other antibiotic treatment. 3. Surgical treatment: at this time you need to incise and drain or pull out the nail for treatment, and change the medicine regularly. Nail groove inflammation perforated the front of the thumb, need to consult a doctor in time, follow the doctor’s instructions for treatment.