Headache with nausea and vomiting is most common in the following diseases: first, vascular headache, which is caused by vasoconstriction and dilatation dysfunction, and can be accompanied by nausea and vomiting in severe cases, but does not cause serious consequences, and can be gradually relieved within minutes or hours; second, intracerebral vascular rupture, which is commonly found in brain parenchymal hemorrhage, ventricular hemorrhage or subarachnoid hemorrhage. High-density shadow, or linear high-density shadow in the subarachnoid space; third, brain tumor, mostly chronic disease progressive aggravation, intracranial pressure increase is obvious when the vomiting, mostly jet, head CT or cranial magnetic resonance examination can find the occupying signs of intracerebral tumor; fourth, intracranial cavernous sinus or venous sinus thrombosis, this disease is generally more difficult to diagnose, appear progressive cranial pressure increase, headache with nausea Vomiting, positive meningeal irritation sign, cranial magnetic resonance examination, sometimes can find the lesion, sometimes need to do further magnetic resonance venous system imaging or enhancement scan; Fifth, central nervous system infection, this kind of headache is mostly accompanied by fever, physical examination also has positive meningeal irritation sign, lumbar puncture will find the cerebrospinal fluid leukocyte count is elevated, and accompanied by significantly elevated pressure.