Gastroesophageal reflux disease (GERD) is a disease in which stomach contents flow back into the esophagus causing symptoms and/or complications such as heartburn, acidity, and chest pain. According to the data, the incidence of GERD is higher in western countries, and the prevalence of GERD can reach 20-30% in the adult population, with about 7% of adults having reflux once a day. The incidence of GERD in China is 6.7% in 2005. Whether in the West or in Asia, the incidence of this disease is on the rise, and there is a tendency of youthfulness, and some patients are easily neglected after getting the disease and cannot get timely treatment, which makes the disease worse. Since the disease is easily confused with chronic pharyngitis, gastritis, lung disease, cardiovascular disease, etc., some patients are often seen in the Department of Five Gases for foreign body sensation in the throat; some are seen in the Department of Respiratory Medicine for chest pain; some are seen in the Department of Cardiology for left anterior chest pain, suspected to be angina pectoris, so it must be differentiated through various examinations. Western medicine treatment is mainly by inhibiting gastric acid secretion and improving gastric power. In Chinese medicine, the identification of the disease belongs to the categories of “acidity”, “regurgitation”, “noisy”, etc. According to the theory of Chinese medicine, “the spleen should rise to be healthy, the stomach should descend to be harmonious”. “Stomach Qi is the basis for the storage, digestion and transmission of food and drink. Because of liver qi offending the stomach, the internal heat, or improper diet, too much spicy food, etc., can lead to the stomach qi should not descend, so that the contents of the stomach reversed upward, resulting in a series of symptoms such as panacidity, heartburn, pain behind the sternum. Taking advantage of the advantages of Chinese medicine, we have formulated the formula of “Descending and Stomach Harmony”, which is based on clearing heat and stomach, stopping acidity and lowering regurgitation to treat GERD, and has achieved good clinical efficacy. “The composition of the formula is based on the ancient formula of Zuo Jin Wan, Xuan Fu Dai Ochre Tang and Xiang Su Drink with the addition and reduction of Wu Bei San. In addition, for difficult cases, a combination of Chinese and Western medicine can be used. In conclusion, gastroesophageal reflux disease is clinically common, with a long course and easy to recur. As long as timely treatment and regular treatment can relieve the symptoms and cure, but we must pay attention to dietary regimen and correct bad habits. The main methods are as follows: 1, regular and quantitative feeding, diet should be light (or eat less and more meals), dinner should not be full, 4 hours before bedtime should not eat. 2, reduce fat intake, cooking should be boiled, stewed, braised mainly, without frying. 3, quit smoking and alcohol. 4, less acidic drinks and sweets, such as lemon juice, chocolate, etc. 5, avoid spicy, stimulating, cold and indigestible food. 6, increase protein intake, such as lean meat, egg whites, milk, soy products, etc.