Red rashes on the palms of the hands may be related to fungal infections, hand eczema, contact dermatitis and other conditions. 1. Fungal infection: If the palm area is infected by fungus, there will be a red rash in the palm area, accompanied by obvious itching symptoms, repeated scratching will lead to the thickening of the skin in the area, and the color may change to dark red. 2. Hand eczema: patients with hand eczema will have small blisters or rashes on their hands, with intense itching, and after the small blisters rupture, there will be yellow liquid outflow, forming yellow scabs. 3. Contact dermatitis: If the palm area comes into contact with medicated adhesive tape, or paint and other allergy-prone substances, an allergic reaction may occur at the contact site, resulting in a red rash and itching. Because of the causes of the disease, the patient is best to go to the hospital dermatology department in a timely manner to check and clarify the cause of the disease.