Diffuse echogenic changes in liver parenchyma generally refers to the abnormal pattern of the liver, and the common ones are liver fibrosis, cirrhosis and fatty liver. 1. Liver fibrosis: Liver fibrosis is generally caused by excessive alcohol intake, circulatory disorders, viral hepatitis, etc. Some patients generally do not have obvious abnormal manifestations, and a few patients tend to have intermittent symptoms, such as loss of appetite, fatigue, right upper abdominal discomfort, etc., after drinking and satiety. 2. Cirrhosis: Cirrhosis is generally caused by long-term cholestasis, immune disorders, viral hepatitis, etc. Early in the patient’s life, a small number of patients generally have no symptoms, some patients will have diarrhea, fatigue, loss of appetite and other digestive symptoms, with the development of the disease, the patient will also have fever, upper gastrointestinal bleeding, liver enlargement and other symptoms. 3. Fatty liver: Fatty liver is generally caused by long-term alcohol consumption, smoking, obesity and other reasons, the disease has a slow onset, usually no symptoms, a small number of patients will appear sleep disorders, fatigue, constipation, right upper abdomen discomfort symptoms, some patients will also appear liver enlargement, a small number of patients will also appear enlarged spleen. The specific causes need to go to the hospital for further examination to determine, after diagnosis under the guidance of the doctor for treatment.