Headache all day long, need to consider the following diseases: a. Vascular headache, is the most common primary headache, but need to pay attention to the headache is paroxysmal, seldom lasts all day, the patient is a paroxysmal distension, throbbing or tingling pain in a fixed area, the head CT has no obvious abnormality. Treatment, you can take oral pain medication symptomatic treatment, such as ibuprofen, naproxen. Second, we need to be alert to whether intracranial occupying lesions have occurred, with tumors being the most common. Because of the slow growth of tumor tissue, compression to the peripheral nerves, producing symptoms of increased intracranial pressure. Therefore, the headache is persistent, all-day pain, and paroxysmal aggravation of the performance, as well as nausea, vomiting, impaired consciousness and so on. Improvement of cranial CT examination can be confirmed, need to consider surgical treatment, internal medicine treatment to dehydration to reduce intracranial pressure. Third, it is necessary to clarify whether the central nervous system infection has occurred, the headache is persistent, but mostly accompanied by fever, positive meningeal irritation signs. Lumbar puncture examination can help to clarify the diagnosis, and antiviral, antibacterial or anti-tuberculosis treatment should be carried out for the pathogen of infection.