Liver hardness of 21kPa suggests a relatively high value of liver hardness, more than 12.5kPa is considered to have early cirrhosis, but also, it may be due to inflammation of the liver as well as fatty liver and other factors. 1. Cirrhosis: In the early stage of cirrhosis, the size of the liver may be normal, but the hardness of the liver is high. If the liver hardness is 21kpa, cirrhosis may occur. 2. Inflammation of the liver: in this case, the liver function will be obviously abnormal, and the hardness of the liver is also higher. 3. Fatty liver: the appearance of fatty liver will affect the hardness of the liver, if the degree of fatty liver is more serious, the hardness of the liver will also increase. In this case, you should consult your doctor in time and improve relevant examinations, such as ultrasound, CT and liver function tests, to determine the cause of the disease and carry out relevant treatment.