Usually, holding urine does not lead to UTI. However, if holding urine for a long time leads to fluid retention in the kidneys, the condition can be serious enough to develop into uremia. Holding back urine means that the urine stored in the bladder exceeds the physiological capacity of the bladder, but consciously does not urinate. People who hold back urine who have a heavy mental burden can induce psychogenic enuresis over time. Prolonged holding of urine can lead to increased pressure in the bladder, retrograde movement of urine in the bladder and bacteria in the urine to the renal pelvis, and diseases such as pyelonephritis; prolonged holding of urine may also lead to fluid retention in the kidneys. As a result of holding urine for too long and for too long, the degree of fluid retention in the kidneys can be further aggravated, and it is possible to suffer from uremia. It is not recommended that patients often hold urine, if there is a desire to urinate, need to be discharged in a timely manner, the emergence of uncomfortable symptoms in a timely manner to the hospital, under the guidance of a professional physician treatment.