Vitamin A cream is a topical cream that is applied to the affected area at bedtime when treating acne. To treat large lesions such as psoriasis and ichthyosis rash, just apply the cream to the affected area. Retinoic acid cream is used clinically for the treatment of acne vulgaris, flat warts, lichen planus, pityriasis rubra, keratosis follicularis, and as an adjunctive treatment for psoriasis. It has a certain degree of irritation, and after topical application, some patients may have mild localized adverse reactions such as tingling, burning, itching, peeling and dryness. The skin can mostly adapt, if the irritation is severe, the drug should be stopped immediately and consult a doctor. Retinoic acid cream is prohibited for pregnant women, lactating women, allergies and eyes, and should not be used in patients with eczema, sunburn, acute and subacute dermatitis, rosacea. In the process of using the drug, pay attention to also avoid sun exposure. Do not use with other drugs at the same time, to avoid drug interactions aggravate the condition. Patients who need retinoic acid cream, should be used in strict accordance with the recommendations of the doctor, to avoid blind use of drugs to cause adverse consequences.