Penile pain may be due to penile injury, urethritis, bladder or urethral stone, foreskin incarceration, etc., which needs to be treated with medication or surgery for the cause. 1. Penile injury: Penile skin, penile corpus cavernosum and urethral corpus cavernosum are damaged due to long-term frequent masturbation, violent sexual behavior, trauma and other factors, which can cause penile pain. In this case, sexual life and masturbation should be avoided to stimulate the penis, and according to the degree of damage to decide whether surgical treatment is needed. 2. Urethritis: Neisseria gonorrhoeae, Chlamydia trachomatis and other pathogens through the urethra after retrograde infection leads to urethral mucosal inflammatory oozing edema, and even localized hemorrhage, causing urethro-penile pain. You can take levofloxacin, azithromycin, tetracycline and other antibacterial drugs. 3. Bladder or urethra stones: stones embedded in the bladder neck or urethra lead to interruption of urinary flow and obvious radiating pain in the penis, resulting in urethral injury and dysuria, need to drink a lot of water to promote the discharge of the stones, and if necessary, through the endoscopic minimally invasive surgery to remove the stones. 4. Circumcision incarceration: men with long foreskin and small foreskin opening have their foreskin turned out under external force, which leads to compression of the coronal groove and affects the blood supply to the glans, resulting in acute edema or even ischemic necrosis of the glans, and thus penile pain. This situation requires immediate surgery to remove the foreskin incarcerated. Penile pain may also be related to penile cancer, penile sclerosis and other factors, it is recommended to consult a doctor for a clear diagnosis and treatment of the cause. Pay attention to the use of medication under the guidance of a physician, not unauthorized use.