Patients only feel coldness in the skin temperature of the affected limb, or mild numbness, and are easily fatigued after activity. Atherosclerotic plaque forms on the inner wall of the arterial vessels, and as the plaque increases and the lumen narrows, the patency of the pipeline is affected, and the blood flow to the lower extremities is reduced, and when the narrowing reaches a certain level or even completely blocked, the blood flow supplying the lower extremities cannot meet the needs, and the symptoms of lower extremity ischemia appear. The following diseases are also causes of the limb susceptible to tinea pedis infections that are not easily controlled: 1. Diabetic foot The diabetic foot is a disease state in which ulcers and gangrene occur in the foot of diabetic patients due to neuropathy that reduces the protective function of the lower limb, and macrovascular and microvascular lesions that cause inadequate arterial perfusion resulting in impaired microcirculation. Diabetic foot is a serious complication of diabetes and is one of the major causes of disability and even death in diabetic patients, which not only causes pain to patients but also adds a huge economic burden to them. 2. Tinea pedis (commonly known as “athlete’s foot” and tinea pedis) is a fungal infection that often occurs unilaterally (i.e., on one foot) and then infects the opposite side weeks or months later. The blisters appear mainly on the belly and side of the toes, most often between the third and fourth toes, and also on the bottom of the foot, where they are small, deep blisters that can gradually fuse into large blisters. The skin damage of tinea pedis is characterized by clear borders that can gradually expand outward. Due to the development of the disease or scratching, vesicles and exudate may appear, or even bacterial infection and pustules may appear. 3, lower extremity arteriosclerosis occlusive disease Arteriosclerosis occlusive disease is a degenerative disease, is the basic pathological process of large and medium arteries, mainly abnormal deposition of cells, fibrous matrix, lipids and tissue fragments, in the arterial intima or middle layer of the complex pathological changes in the process of proliferation. Among peripheral vascular disorders, almost most of the narrowing, occlusive or aneurysmal lesions of arteries are caused by atherosclerosis. Atherosclerotic lesions are generally systemic disorders that occur in certain large and medium-sized arteries, such as the lower abdominal aorta, iliac artery, femoral artery, and popliteal artery, but rarely in the upper limb arteries. The arteries are thickened, stiffened, with atheromatous plaque and calcification, and may be followed by thrombosis, resulting in narrowing or occlusion of the arterial lumen and ischemic symptoms in the limbs. The affected limb has clinical manifestations such as coldness, numbness, pain, intermittent claudication, and ulceration or necrosis of the toe or foot. Sometimes the stenosis or occlusive lesions are segmental and multiplanar in nature, most often occurring at the beginning of the bifurcation of the artery and the posterior wall of the lumen, and the bend of the arterial trunk is also more often involved.