Tremor of the hands alone cannot be diagnosed as Parkinson’s disease. This is because there can be many causes of tremors in the hands. It appears at rest and decreases or disappears with movement, mostly more pronounced in the distal extremities. Resting tremor is one of the clinical manifestations of Parkinson’s disease. Resting tremor in Parkinson’s disease is often accompanied by increased muscle tone, which can be found during examination as cogwheel-like or lead pipe-like straightening, easily detected during head and neck extension and flexion and passive movement of the elbow and wrist joints. The clinical manifestations and preliminary diagnosis of bilateral tremor symptoms are mainly distinguished from Parkinson’s disease diagnosis, which can be made based on the clinical manifestations and the type of etiology. 1, post-encephalitis Parkinson’s syndrome: commonly referred to as lethargic encephalitis due to Parkinson’s syndrome, has not been reported for nearly 70 years, so the encephalitis due to post-encephalitis Parkinson’s syndrome also disappeared. In recent years, it has been reported that patients with viral encephalitis can have Parkinson’s-like symptoms, but the disease has obvious symptoms of infection and can be accompanied by cranial nerve palsy, limb paralysis, convulsions, coma and other symptoms of neurological damage, and the cerebrospinal fluid can have a mild to moderate increase in cell count, increased protein, and decreased sugar. The Parkinson’s-like symptoms are relieved when the disease is in remission, which can be differentiated from Parkinson’s disease. 2, hepatomegaly: recessive hereditary disease, about 1/3 have family history, adolescent onset, may have extrapyramidal symptoms such as increased limb tone, tremor, mask-like face, twisting spasms. The disease is characterized by liver damage, decreased corneal K-F ring and serum copper blue protein. It can be differentiated from Parkinson’s disease.