Cranial defects are becoming more and more common, some people are injured by accidents and some people are left with cranial defects because of brain surgery, but no matter what the reason is, cranial defects should be taken seriously, because the defective parts usually do not grow well on their own, and they may also collapse or bulge out and deform after a long period of time. Of course, cranial defects can not only have this effect, cranial defects will be very ugly after the appearance of the skull, the patient’s heart will be very stressful; and cranial defects will lead to intracranial pressure becomes unstable, on the cranium of the various life activities will have an impact; in addition to the cranial defects, intracranial tissues are directly exposed, once the second collision, there will be a risk of life-threatening. Cranial defects really can not be careless, especially if the defect area is large, it is more important to go to the hospital in time to do cranial repair surgery, not to mention that cranial repair surgery is not a major surgery, safety is relatively high, the successful repair of the patient is of great benefit to the patient. However, the important point of doing skull repair surgery is the choice of materials, good materials to achieve better repair results. At present, many hospitals are using titanium mesh material, titanium mesh material is relatively inexpensive, but the postoperative effect is not very satisfactory, and there may also be some complications after surgery. The polyether ether ether ketone peek material we now use is different, this is a new type of polymer material, its performance is very good, but also personalized three-dimensional reconstruction design and production, can better restore the shape of the skull. What is the meaning of three-dimensional reconstruction of the skull? Many patients do not understand what this means, in fact, is to do a three-dimensional reconstruction of the skull before the operation CT scan, so that the patient can be captured to the detailed three-dimensional data of the skull, and then according to the patient’s specific situation to personalized precision customization, so that the material can be made out of precise embedded with the bone window, a tight fit, will be more natural and beautiful.