If the result of non-invasive DNA test suggests the presence of sex chromosome bias, the pregnant woman should undergo amniocentesis; if the amniocentesis test suggests the presence of sex chromosome bias, the pregnancy can be terminated if necessary. Non-invasive DNA test is mainly used to screen for abnormalities in the number of fetal chromosomes 21, 18, and 13, and if the test suggests that there is a sex chromosome abnormality, further amniocentesis is usually required. Amniocentesis can do fetal karyotype analysis to clarify whether the fetus indeed has sex chromosome hypoplasia. If it is clear that the fetus may have abnormalities such as underdeveloped or missing sex organs after birth, the pregnancy can be terminated if necessary. If a pregnant woman discovers the existence of sex chromosome deficiency during pregnancy test, it is recommended to go to the hospital in time, improve the examination to clarify the cause of the disease, and then give targeted treatment or standardized treatment.