The third dose of the New Crown vaccine does not normally affect the liver. The third vaccination will stimulate the body to produce an immune response and greatly increase the amount of antibodies to the new coronavirus in the body. However, some adverse reactions may occur during the third vaccination. The main and common adverse reactions include redness, swelling and pain at the vaccination site, mild fever, loss of appetite, poor mental status and drowsiness, etc. Liver damage is usually not observed. The safety and efficacy of XKV vaccine have passed the relevant national standards, and those who meet the indications for vaccination are vaccinated according to the prescribed procedures and dosage, which usually will not cause any damage to the organs of the organism. Contraindications to the third dose of the vaccine include allergy to the vaccine, or an exacerbation of the disease. After vaccination, a period of observation is required, and if serious adverse reactions occur, prompt medical attention is required.