It is very common to have knee pain during the course of a cold, and the causes of such symptoms are mainly the following: 1, it may be a cold at the same time as the cold, the patient’s cold itself may be caused by wind and cold, at this time, if there is a cold in the knee joint at the same time, it will cause aseptic inflammation inside the knee joint, which will lead to knee pain; 2, it may be the inflammatory reaction caused by the cold, for example, during the onset of influenza In addition, the cold will lead to a significant increase in inflammatory mediators in the body, which will aggravate the inflammation of the knee joint, such as osteoarthritis, synovitis and other diseases at this time will aggravate and lead to soreness; 3, it may also be caused by autoimmune diseases, such as upper respiratory tract infection induced rheumatism, rheumatoid arthritis, which will also lead to soreness. Rheumatoid and rheumatoid arthritis, which can also involve the knee joint and lead to soreness.