Diabetic maculopathy is a skin disease specific to diabetic patients. With the increasing incidence of diabetes, the widespread use of insulin and oral hypoglycemic drugs, and the prolongation of patient survival, there is an increasing trend in the incidence of complications and maculopathy. Clinically, there are three general types: most of them are spontaneous, painless, and tense herpes clear blisters, followed by hemorrhagic and painful blisters. The mechanism of blistering has not been elucidated, and most blisters can heal spontaneously, but once infected, diabetic foot ulcers and gangrene can develop secondary to serious consequences, even amputation. The mechanism of blistering has not been elucidated, and may be related to local metabolic disorders, trauma, etc. At present, there is no special treatment method. In order to prevent local infection, some advocate the use of cold compresses, fluid pumping, clean drug changes and other methods, the efficacy is not sure. Our department adopts the method of differentiating internal and external treatment with Chinese medicine to achieve remarkable efficacy. Diabetic patients can suffer from spleen qi deficiency due to many factors such as poor diet, excessive thinking, abnormal work and rest, excessive use of cold and cold, and spleen deficiency, which can lead to internal generation of water and dampness and abnormal ascending and clearing. This is the basis for the diagnosis of the disease, and the treatment is divided into different types.