Diabetic gastrointestinal neuropathy is mainly caused by functional changes in the gastrointestinal nerves due to poor control of diabetes. Generally speaking, diabetic gastrointestinal neuropathy mainly causes gastrointestinal motor disorders, and the performance may be different depending on the affected area. First, gastric lesions: neuropathy can cause gastric paralysis, which is customarily called gastroparesis in medicine. The contents of the stomach cannot be emptied into the intestines, and one may often feel a lack of appetite, belching, nausea, vomiting, bloating, etc., and the stomach becomes full as soon as one eats. Second, small intestine lesions: due to the toxic effect of sugar, the nerves that govern the small intestine become diseased over time, and diarrhea may suddenly occur, as little as 3 to 5 times a day, as much as 20 to 30 times a day, usually more serious at night, in large amounts, like watery diarrhea, but generally no abdominal pain, blood in the stool, sometimes for several days, sometimes for several weeks, this situation should also pay attention to whether it is caused by bicalutamide drugs. Third, colorectal lesions: the most common may become constipation, or even cause intestinal obstruction. Some patients have alternating constipation and diarrhea. It is often thought of as irritable bowel syndrome, but is actually caused by neurological disorders caused by diabetes. Knowing about diabetic gastrointestinal neuropathy can help improve prevention and timely detection of the