Hepatitis B five 45 long-term non-negative harm need to be combined with other test results, if the hepatitis B surface antigen negative, that is infected with hepatitis B has been cured, do not have to worry. If hepatitis B surface antigen positive, need to further improve the liver function and liver ultrasound and other tests, the test results are abnormal need to comply with the doctor’s instructions for treatment, and regularly to the regular hospital for re-examination, if not treated, it will further damage the liver, there is a risk of developing into cirrhosis and liver cancer. This situation requires further examination of liver function and liver ultrasound, if the test results are abnormal, you need to follow the doctor’s instructions for antiviral treatment. If the results are abnormal, antiviral treatment should be prescribed by the doctor. If left untreated, the liver damage will further develop and there is a risk of cirrhosis and liver cancer. If Hepatitis B surface antigen is negative and Hepatitis B V 45 is positive, it means that you have been infected with the Hepatitis B virus, but now you are cured, so you don’t need to worry too much. Hepatitis B 45 positive patients are advised to consult a doctor for further diagnosis and treatment under the guidance of a physician.