Eyes with a grayish feeling should first determine whether there is a refractive interstitial clouding lesion, such as keratitis-induced corneal clouding, scarring, lens clouding, etc. It may also be a macular site disease that causes darkening and discoloration of vision and other symptoms, and relevant tests such as slit lamp should be performed, which can determine whether there is a corneal lesion. Most patients will experience pain, photophobia, vision loss and other discomforts during the period with inflammatory infection. The infecting pathogens are different and the corneal lesions are changed differently, which usually require topical eye drops, systemic with infusion and other treatments. There are more kinds of possible diseases of macular degeneration, if the visual impact is small and the patient is young, consider it may be central plasmacytoid chorioretinopathy, this disease has a certain possibility of self-healing, but after that there may be long-term residual abnormal visual changes.