Generally speaking, after the surface antigen has turned negative, it means that the hepatitis B disease has basically been cured, and the hepatitis B virus DNA will be cleared with it. However, this is not absolute, if the patient suffers from hidden hepatitis, then the DNA may take some time to be gradually cleared, the exact time is related to the severity of the disease.
Surface antigen is one of the main indicators for detecting hepatitis B virus infection. The conversion of hepatitis B surface antigen to negative signifies that most of the hepatitis B virus has been eliminated from the body, indicating that the patient’s condition has basically recovered, which is usually accompanied by the clearance of hepatitis B virus DNA.
However, if the patient suffers from hidden hepatitis, even if the surface antigen is negative, hepatitis B virus DNA can still be detected in the body, which has not been completely eliminated, and there is also an increase in aminotransferase, which indicates that the patient has not completely recovered, and the patient’s condition may still deteriorate afterward, or even lead to liver cancer.
Therefore, even if the surface antigen of hepatitis B is negative, patients should continue to observe other markers of hepatitis B virus, such as hepatitis B virus DNA, and if the virus DNA is not completely negative after half a year, then it is necessary to go to the hospital in time to receive examination and actively cooperate with the doctor’s treatment.