The significance of checking hormone six for pituitary microadenoma is mainly to clarify which type of microadenoma it is, so that the appropriate treatment can be chosen according to the specific type. Pituitary microadenoma is a kind of intracranial tumor with a diameter of less than 10mm, which is classified into functional microadenoma and non-functional microadenoma, and the significance of checking hormone 6 is mainly to determine the type of adenoma according to the results of the examination. Microadenomas can be classified into prolactin adenomas, growth hormone adenomas, adrenocorticotropic hormone adenomas, thyrotropic hormone adenomas, gonadotropin adenomas, mixed adenomas, eosinophilic stem cell adenomas, and lactotropic growth hormone adenomas according to the function of their secretion, and the test results of Hormone 6 can clarify which hormone is abnormal and which type of adenomas it is according to the results of this test. In the clinic with pituitary microadenomas should follow the doctor’s instructions for examination, according to the clinical symptoms and other test results of a comprehensive diagnosis, to clarify the specific type, targeted treatment, to avoid the wrong treatment.