Pain in the flesh next to the nail requires general treatment, medication, and surgery depending on the specific cause. This condition is considered to be due to compression or the penetration of foreign objects such as wood chips or glass into the local skin. It may also be caused by the presence of ingrown nails, onychomycosis and other conditions. For extrusion or foreign objects, it is necessary to promptly disinfect and gently remove the foreign object. Then under the guidance of the doctor to take anti-inflammatory drugs such as amoxicillin and other antibiotics to prevent infection, take ibuprofen, diclofenac sodium and other drugs to relieve pain; bleeding people injected tetanus antitoxin to prevent tetanus. In the case of ingrown nails, if the symptoms are mild, you can use a cotton ball pad in the nail plate between the nail grooves, so that the nail plate and the soft tissue to separate, so that the nail side edge of the pressure on the surrounding tissues to reduce. If treatment is ineffective, you need to seek medical attention for surgical treatment. In the early stages of nail fissure infection, antibiotics such as amoxicillin and cefaclor can be taken and drugs such as topical mupirocin ointment can be used to control the infection. If there is abscess formation, incision and drainage is needed, and regular medication change treatment.