In children with multiple abnormal signal shadows in the posterior horn of bilateral lateral brain, myelin dysplasia may be cerebral leukodystrophy, which can be of several types, including heterochromatic cerebral leukodystrophy, globoid cell cerebral leukodystrophy, and adrenal cerebral leukodystrophy, etc, and may also be caused by physiological factors.
1. Heterochromatic leukoencephalic dystrophy: Usually, the onset of the disease occurs at the early stage of infancy, with low muscle tone, large movements, developmental delays, mental retardation, bedriddenness, increased muscle tone, etc. In the later stage, there will be swallowing difficulties, feeding difficulties, and finally, convulsive episodes, and a state of dementia.
2. Spherocyte leukoencephalomalacia: the onset is earlier, around four months, after the symptoms appear, at first, the muscle tone is reduced, and gradually the resistance is increased, tonicity, vision loss, and seizures.
3. Adrenoleukodystrophy: this is a kind of lipid metabolism disease. It is mainly seen in male patients and usually develops after three years of age. It is mainly characterized by mental retardation, paralysis, convulsions, and in the later stage, symptoms of increased intracranial pressure may appear, which are manifested as severe headache, vomiting, lethargy, and personality changes.
4. Physiological factors: If there is no symptom, it may be caused by physiological factors. Generally, with the growth of the child’s age, the child’s myelin sheath can gradually develop and mature.
There are other causes of myelin dysplasia in children with multiple abnormal signaling shadows in the posterior horn of the lateral brain bilaterally, so it is recommended to consult a doctor in time to find out the cause and treat the cause.