Ulcerated bulge lesions in the greater curvature of the body of the stomach are first pathologically examined to clarify the cause of the disease and then treat the symptoms. When an ulcerated bulge in the greater curvature of the body of the stomach is found to have lesions, the first thing to do is to take tissue from the lesion for pathological biopsy. If the result of biopsy is benign, the use of acid suppressants and gastrointestinal mucosal protective agents can be used to assist in the treatment. After the condition is stabilized, the patient can be further examined for the presence of Helicobacter pylori infection, and patients with Helicobacter pylori infection generally need to use quadruple therapy bactericidal treatment under the guidance of the doctor. If the result of pathological biopsy is malignant, surgical treatment or radiotherapy or immunotherapy should be chosen as early as possible according to pathological staging. In the process of treatment, ensure a good diet, do not eat stimulating food, pay more attention to rest. When the ulcerated bulging lesions in the greater curvature of the stomach body should go to the hospital as soon as possible for pathological examination, to clarify whether it is a malignant disease, and early symptomatic treatment, so as not to delay the condition and affect health.