The efficacy of Trimethoprim Cream is antibacterial, anti-inflammatory, anti-allergic, anti-itching, etc. Side effects mainly include allergic reactions, burning sensation of the skin, itching, and pins and needles sensation. Trimethoprim cream is a compound preparation made of miconazole nitrate, tretinoin acetate and neomycin sulfate, which synergistically exerts the effects of antifungal, antibacterial, anti-inflammatory, anti-allergic and antipruritic, and is suitable for the treatment of seborrheic dermatitis, contact dermatitis, neurodermatitis, eczema, tinea cruris, tinea cruris, ringworm, and other diseases. The drug should be contraindicated in people who are allergic to the product, while patients with hypertension, osteoporosis, heart disease, liver insufficiency should be used with caution. Allergic reactions, burning sensation, itching, pinprick sensation of the skin may occur after the use of the drug, and long-term use may cause local skin atrophy, hyperpigmentation, hirsutism and other adverse reactions. Specific medication should be under the guidance of a specialist, not unauthorized use of medication.