Oral antithrombotic therapy is mainly used for patients with atherosclerosis, unstable angina, heart attack, atrial fibrillation, cerebral thrombosis, deep vein thrombosis, post-stenting and post-heart valve replacement. Commonly used clinical drugs include aspirin, clopidogrel and warfarin. Dental clinics often encounter such patients requesting tooth extraction. Currently, there is no clear opinion on the need to discontinue anticoagulant medications prior to tooth extraction. However, there is a growing recognition that the risk of bleeding in patients on anticoagulation must be carefully assessed along with the risk of thrombosis. The risks associated with discontinuation or dose reduction often outweigh the risk of postoperative bleeding. Since tooth extraction surgery itself is less invasive and superficial, the chance of serious uncontrollable bleeding after surgery is low, and conditions are available to enhance hemostasis through local measures, some scholars at home and abroad prefer to perform simple alveolar surgery such as tooth extraction and dental implant without drug discontinuation in recent years. Zhang Dong, Department of Oral and Maxillofacial Surgery, Qilu Hospital, Shandong University