Spots on hands may be related to coffee spots, hyperpigmentation spots, age spots, etc. They should be removed by medication (hydroquinone cream, etc.) as well as physical therapy according to the cause. 1. Coffee spot: it is related to congenital factors and manifests itself as a symmetrically distributed spot on the back of the hand. You can use laser to get rid of the spots, using the wavelength of laser to pulverize the melanin of the spots to form fine particles, which will be discharged out of the body along with the body. 2. Hyperpigmentation spots: it may be that the hands used to suffer from eczema or dermatitis, and after inflammation stimulation and the use of medication, it will cause stimulation to the local skin and form hyperpigmentation. You need to pay attention to sun protection, most of them will recover in 3 to 6 months, and apply hydroquinone cream and other medicines if necessary, but it may not be able to be completely removed. 3. Age spots: it has some relationship with skin photoaging and belongs to a physiological phenomenon. It can be improved by using carbon dioxide laser to remove spots, cryotherapy and other methods. However, it is necessary to pay attention to sun protection after treatment to avoid anti-blackness. It is suggested that patients with spots on hands should consult the doctor in time, do systematic examination and follow the doctor’s instruction.