Small liver function and large liver function mainly refer to the difference in the number of check items, that is, compared with small liver function, large liver function check items are more comprehensive and detailed, which can more fully reflect the synthesis, metabolism, transformation, excretion and other related functions of the liver. The specific items of large liver function test and small liver function test differ from hospital to hospital. Generally speaking, the items of small liver function test mainly include aminotransferase, bilirubin, albumin and so on. In addition to the above indicators, large liver function tests also include total protein, prealbumin, globulin, albumin-globulin ratio, glutamate-glutamate ratio, glutamyl transpeptidase, alkaline phosphatase, cholinesterase, total bile acids, adenosine deaminase, sialic acid, glutamate dehydrogenase, and so on. Clinically, different tests can be selected according to different needs, such as small liver function for normal people, while for people with a history of liver disease or those who need to undergo surgery related to the hepatobiliary system, they need to undergo a more comprehensive large liver function test.