Patients with a large local bulge when the injection, according to the specific reasons for the bulge, the clinic can often take different treatment methods: a. If the patient has an allergic allergic reaction to the local injection of drugs, there is a significant swelling of local tissue, bulging bags. At this time, the patient can locally rub dermaplanin ointment, oral paracetamol or loratadine and other anti-allergic drugs to reduce the body allergic allergic reactions, can promote the rapid absorption of local large bags, subside. Second, if the patient because of the local vascular elasticity is poor, the injection with more venous fluid leakage and cause obvious bulge. Patients are often accompanied by local tissue swelling, pain, can be given as soon as possible 50% magnesium sulfate or Ole gel local topical, oral Mizarin, intravenous furosemide to strengthen the diuretic can improve local blood circulation, to promote the bulge symptoms faster subside.