Nifedipine extended-release tablets overdose requires immediate attendance at the emergency department of the hospital for supervised pressure-raising treatment. When nifedipine extended-release tablets are overdosed, there will be a significant decrease in blood pressure, or even cardiogenic shock, resulting in insufficient blood supply to the tissues and organs of the whole body, especially the brain, causing blurred consciousness or even coma. Therefore, when an overdose of nifedipine extended-release tablets is mistakenly taken, shortly after the drug is taken you can take to stimulate the throat with your hand to induce vomiting and reduce the absorption of the drug, and then you should lie flat to increase the blood supply to the brain. At the same time immediately to the hospital, blood pressure monitoring, systolic blood pressure is higher than 90mmHg, can be first rehydration therapy; lower than 90mmHg, the appropriate use of antihypertensive drugs, such as dopamine, norepinephrine, etc., until the body’s metabolism of nifedipine to the normal level. Hypertensive patients in the use of nifedipine extended-release tablets, must be under the guidance of a specialist physician medication, not arbitrarily increase the dosage, before taking the drug again to determine the specifications and dosage of the drug, in order to avoid accidents.