Rescue measures for acute poisoning by barbiturates: 1. Immediate gastric lavage for orally poisoned patients, give activated charcoal after gastric lavage, and then give magnesium sulfate to induce diarrhea. 2. Comatose patients should keep the airway open and continue to breathe oxygen. If necessary, tracheotomy or intubation, artificial respiration. And pay attention to warmth, prevention and treatment of pulmonary infections. 3, alkalinize urine with 5% sodium bicarbonate 250ml intravenous drip, which can increase the body’s phenobarbital excretion from the urine. In addition, rehydration and diuresis are also beneficial to the excretion of toxic substances. Also correct water, electrolyte and acid-base disorders. Patients presenting with cardiac failure are given cidilan instantly.4. In case of peripheral circulation failure, maintenance by rehydration or vasoactive drugs.5. Patients with large amount of toxicity are treated with blood purification, either hemodialysis or hemoperfusion.6. Other symptomatic and supportive treatment.