Acupoint injection is a method to prevent and treat various diseases by injecting appropriate amounts of Chinese or Western medicine into meridians, acupoints or pressure points, or subcutaneous positive reactive objects. This treatment method is guided by the doctrine of meridians, acupuncture points and drug effects, which are organically combined to bring about clinical efficacy. Since its creation in the 1950s, this method has been widely used in various clinical departments because of its precise clinical efficacy, and it has also achieved satisfactory results in the treatment of many diseases in dermatology, such as chronic urticaria, eczema, and neurodermatitis. Acupoint injection has the following two characteristics: first, the same point is different from the drug, which means that the acupoint injection has drug specificity, and the same point is injected with different drugs to produce different therapeutic effects. Second, the same drug and different points, that is, different points injected with the same drug will also produce different effects. Some scholars have explored the mechanism of acupoint injection from the perspectives of meridians being porous media channels, meridians having semiconductor-like properties, and the influence of trace elements on the efficacy of acupuncture points. First, meridians are porous media channels with a continuous liquid phase predominant, through which acupuncture point drug administration can specifically act on target tissues. That is, the drug is restrained in the meridians and does not diffuse outside the meridians, thus ensuring the concentration of the drug. Coupled with the transport effect of tissue fluid along the meridians, the drug can reach the disease place faster, and this delivery channel has a higher concentration of drug action than the systemic diffusion through blood, which has good specificity, less side effects, and better therapeutic effects. Secondly, the blood contains a variety of trace elements, antibodies, hormones, enzymes and other media, the drug injected into the acupuncture points through the above media continue to slowly stimulate the body’s own immune system, prompting the release of more immunoglobulins, antagonize histamine, inhibit metabolic reactions and reduce capillary permeability, improve lymphatic circulation, regulate endocrine disorders, enhance microcirculation, nourish the skin, improve the ability to resist disease, thereby anti-inflammatory It can reduce inflammation, swelling, exudation, nourish the skin and promote the fading of skin lesions. Acupuncture point injection is different from the general drug delivery mechanism and route, because the acupuncture point drug effect has the original pharmacodynamic properties of the drug, but also has a rapid effect, before absorption or effective blood concentration, and the drug effect can be the same as or even more than intravenous injection without absorption process, this rapid and powerful initial drug effect is not significantly related to blood concentration, and also not significantly related to the integrity of the nervous system, indicating that acupuncture point injection The drug effect is related to meridian involvement.