What is the best medication for treating gastric ulcer depends on what the cause of the ulcer is. If the cause of gastric ulcer is H. pylori infection, eradication of H. pylori is the best solution to treat gastric ulcer. There are triple therapy and quadruple therapy to eradicate H. pylori, the specific drugs are two antibiotics, plus a proton pump inhibitor, or a bismuth preparation on top of the triple therapy. As an example, it could be amoxicillin plus metronidazole, omeprazole, and quadruple therapy would require the addition of colloidal bismuth on top of that, just to give an example, there are other options for specific medications. If the cause of gastric ulcer is not Helicobacter pylori, in the treatment of the general choice of drugs to reduce gastric acid, plus gastric mucosal protective agent can be, to reduce gastric acid drugs are now more recommended is the proton pump inhibitors, drugs such as omeprazole, rabeprazole, pantoprazole, lansoprazole, esomeprazole and so on, mucosal protective agent with aluminum thioglycollate, bismuth pectin, rebapartite and so on, are available. Each person does not respond to the drugs quite the same, and most people can cure their ulcers by choosing these drugs.