Yellowing of the newborn’s teeth is most commonly associated with jaundice in the newborn. Neonatal jaundice can manifest as yellowing of the skin mucous membranes and sclera. In this case, a newborn transdermal jaundice test is first required, and depending on the value of jaundice, different treatment options are adopted. If the jaundice value is within the range of physiologic jaundice, no special treatment is needed, and physiologic jaundice in full-term infants will subside on its own within two weeks. If the jaundice value is high, the jaundice is pathological and requires prompt intervention. Commonly used treatments include blue light irradiation to reduce jaundice, intravenous application of albumin to reduce free bilirubin, and hemolytic jaundice requiring the application of gammaglobulin to block hemolysis. Pathological jaundice must be treated promptly to avoid causing bilirubin encephalopathy.