Abnormal ECG t-wave may be a physiological phenomenon that does not require treatment, or it may be a disease such as myocardial ischemia, which is usually treated with medication such as nitroglycerin. ECG t-wave is a lower and longer wave generated by ventricular repolarization. Changes in the external environment and one’s own state may cause changes in the t-wave, such as women’s t-wave being lower than men’s, or mental stress, etc., which may cause the t-wave to undergo physiological changes. However, myocardial ischemia, myocardial infarction, coronary artery disease, hyperkalemia and hypokalemia may also lead to ECG t-wave abnormality, which can be generally improved by drugs such as nitroglycerin to diastole the blood vessels, β-blocker to slow down the heart rate to improve the metabolism and so on. The use of such drugs may lead to headache, dizziness and other discomforts, suffering from sinus block, early myocardial infarction and other patients and allergy is prohibited. If the ECG t-wave abnormality occurs, please go to the hospital and ask the doctor for diagnosis, and determine the specific treatment according to the diagnosis. If necessary, please use the drug under the guidance of a physician.