Amlodipine besylate can usually be taken together with Irbesartan. Amlodipine benzenesulfonate belongs to calcium channel blockers, which can lower blood pressure by reducing the contractile response of resistance vessels, and can be taken together with Irbesartan to enhance the antihypertensive effect. Adverse effects of amlodipine benzenesulfonate include flushing, edema, nausea, headache, etc. Amlodipine benzenesulfonate is contraindicated in allergic patients. Irbesartan belongs to the angiotensin II receptor antagonist, by blocking vasoconstriction and reducing sodium retention to reduce blood pressure. Irbesartan adverse reactions include dizziness, facial flushing, nausea, and dyspepsia. Irbesartan is contraindicated in women with allergies, mid to late pregnancy and lactation. Amlodipine besylate can usually be taken together with Irbesartan, and the combination of the two can effectively lower blood pressure. However, the combined use of drugs should be standardized under the guidance of a doctor, not blindly use the drug. If there are any adverse reactions after taking the drug, you should go to the hospital in time for timely treatment, and follow the doctor’s instructions for the use of medication.